The T. evansi genome database is currently under development. Genome assemblies, annotations, and comparative analyses will be made available as soon as they are completed.
What is T. evansi?
Trypanosoma evansi is the causative agent of Surra, a wasting disease that affects a wide range of mammals including horses, camels, cattle, and dogs. It is transmitted mechanically by biting flies (Tabanidae) and affects livestock across Asia, Africa, and Latin America.
Kinetoplast DNA
Notably, some T. evansi strains have lost maxicircle kinetoplast DNA due to mutations in the RBP6 gene, which encodes a mitochondrial editing factor. This makes T. evansi a unique model for studying kinetoplast evolution.
Coming Features
The database will include genome browsers with interactive SVG viewers, dotplots for synteny analysis, Circos visualizations, BLAST search tools, and downloadable annotation files in standard formats (GFF3, FASTA, GenBank).
Publications
Genome sequence of a Trypanosoma evansi isolate from a dog in Uruguay.
Vet Parasitol Reg Stud Reports (year). https://doi.org/10.1128/mra.00568-26
The first case report of trypanosomiasis caused by Trypanosoma evansi in Uruguay.
MRA (year). https://doi.org/10.1016/j.vprsr.2017.11.002